Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8339251 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 8 Pages |
Abstract
⸠1,25-Dihydroxyvitamin D3 alters expression of FoxO and SESN in osteoblasts. ⸠Vitamin D receptor binds to functional VDRE in SESN1. ⸠FoxO or SESN knock-down does not affect growth inhibition by 1,25-dihydroxyvitamin D3. ⸠1,25-Dihydroxyvitamin D3 induces increased ROS in FoxO knock-down osteoblasts.
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Authors
Guy Eelen, Lieve Verlinden, Mark B. Meyer, Rik Gijsbers, J. Wesley Pike, Roger Bouillon, Annemieke Verstuyf,