Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8339258 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 5 Pages |
Abstract
⸠We performed genome-wide ChIP-seq analysis on coactivators and corepressors during 1,25(OH)2D3 treatments. ⸠The coactivator SRC-1 was most highly correlated with VDR/RXR during 1,25(OH)2D3 activation. ⸠Corepressors NCoR and SMRT were also recruited to activation complexes near genes stimulated by 1,25(OH)2D3. ⸠NCoR showed an increased association with VDR only after 1,25(OH)2D3 treatment, as exemplified by the gene c-FOS.
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Authors
Mark B. Meyer, J. Wesley Pike,