Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8339493 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 13 Pages |
Abstract
⺠We cultured fibroblasts from breast cancer (CAFs) and paired normal tissue (NAFs). ⺠Genes differentially expressed were analyzed in CAFs and NAFs treated with 1,25D. ⺠In CAFs, genes coded for proliferation inhibition and anti inflammation effects. ⺠In NAFs induced genes coded for anti apoptosis, immune defense and detoxification. ⺠Common genes showed different co-expression by networks and interactome analysis.
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Authors
Laura Tojeiro Campos, Helena Brentani, Rosimeire Aparecida Roela, Maria Lucia Hirata Katayama, Leandro Lima, CÃntia Flores Rolim, CÃntia Milani, Maria Aparecida Azevedo Koike Folgueira, Maria Mitzi Brentani,