| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8339533 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 8 Pages |
Abstract
⺠Transactivation of CAR, PXR, or FXR in isolated Leydig cells using known agonists. ⺠Expression of several genes increased including CYB5A, CYB5R1, HSD17B4, and RDH12. ⺠Transactivation of CAR, PXR or FXR decreased sex steroid production. ⺠Transactivation of CAR or PXR increased 16-androstene steroid production.
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Authors
Matthew A. Gray, E. James Squires,