| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8339547 | The Journal of Steroid Biochemistry and Molecular Biology | 2013 | 11 Pages |
Abstract
⺠11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) is a critical target in obesity. ⺠The tissue-specific expression of 11β-HSD1 (HSD11B1) was obscure. ⺠This is the first report on the regulation of 11β-HSD1 expression by miRNAs. ⺠We could detect both miR-561 and -579 in human total liver RNA by RT-PCR. ⺠The two miRNAs may have a potential role in glucocorticoid associated diseases.
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Authors
Yanyan Han, Claudia A. Staab-Weijnitz, Guangming Xiong, Edmund Maser,