Article ID Journal Published Year Pages File Type
8339572 The Journal of Steroid Biochemistry and Molecular Biology 2012 8 Pages PDF
Abstract
► Wild type p53 is necessary for E2-induced apoptosis in non-malignant colonocytes. ► E2 treatment enhances p53 accumulation in non-malignant colonocytes. ► Pro-apoptotic, p53 target genes are enhanced by E2 treatment. ► E2 treatment reduces radiation induced DNA damage foci in these cells.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
P53 mediates estradiol induced activation of apoptosis and DNA repair in non-malignant colonocytes
Authors
, , , ,