Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8339586 | The Journal of Steroid Biochemistry and Molecular Biology | 2012 | 6 Pages |
Abstract
⺠We studied postmenopausal women submitted to atorvastatin and hormone replacement. ⺠We evaluated effects of treatments and SNPs on modulation of APOE expression. ⺠APOE and LXRA expression are positively correlated before and after treatments. ⺠APOE expression on mononuclear cells is down-regulated by atorvastatin treatment. ⺠APOE down-regulation by atorvastatin is influenced by APOE genotypes.
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Authors
Mustafa H. Issa, Alvaro Cerda, Fabiana D.V. Genvigir, Selma A. Cavalli, Marcelo C. Bertolami, Andre A. Faludi, Mario H. Hirata, Rosario D.C. Hirata,