Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8339603 | The Journal of Steroid Biochemistry and Molecular Biology | 2011 | 5 Pages |
Abstract
⺠Inappropriate activation of PPARγ by environmental chemicals contributes to obesity. ⺠Many natural products activate PPARγ but are not necessarily linked to adipogenesis. ⺠PPARγ is a vulnerable target of obesogens during prenatal programming events. ⺠Obesogens could alter lineage-specific histone modifications in stem cells. ⺠Obesogens could bias PPARγ towards recruitment to adipogenic gene enhancers.
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Authors
Amanda Janesick, Bruce Blumberg,