Article ID Journal Published Year Pages File Type
8339603 The Journal of Steroid Biochemistry and Molecular Biology 2011 5 Pages PDF
Abstract
► Inappropriate activation of PPARγ by environmental chemicals contributes to obesity. ► Many natural products activate PPARγ but are not necessarily linked to adipogenesis. ► PPARγ is a vulnerable target of obesogens during prenatal programming events. ► Obesogens could alter lineage-specific histone modifications in stem cells. ► Obesogens could bias PPARγ towards recruitment to adipogenic gene enhancers.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, ,