| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8339615 | The Journal of Steroid Biochemistry and Molecular Biology | 2011 | 6 Pages |
Abstract
⺠The arylhydrocarbon receptor (AhR) is a ligand-dependent transcription factor mediating the adverse effects of dioxins. ⺠Modulation of estrogen/androgen signaling by dioxins is exerted in part through direct association of AhR with estrogen or androgen receptors. ⺠AhR assembles CUL4B-based ubiquitin ligase complex and promotes the degradation of ERα and AR.
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Authors
Fumiaki Ohtake, Yoshiaki Fujii-Kuriyama, Kaname Kawajiri, Shigeaki Kato,