Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8339960 | Journal of Traditional Chinese Medical Sciences | 2016 | 22 Pages |
Abstract
Qijian Heji, with proportion of 3:1, could significantly reduce the blood glucose values in kk mice, animal experiment results verified the accurate prediction of network pharmacology, and at the same time, it is verified there was a certain therapeutic effect about the combination of the two herbs on reducing the glucose value. Animal experiments and RT-PCR results showed that Qijian Heji conducted a hypoglycemic effect by modulating estrogen receptor (ESR1) and renin (REN) expression.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Kun Chen, Dong Deng, Youliang Huang, Xiaoyun Ma, Xueli Li, Wenting Zhang, Zhiyong Li, Yang Liu, Wei Wang, Jianxin Chen, HuiHui Zhao,