Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8340283 | Methods | 2016 | 8 Pages |
Abstract
RNAComposer is a user-friendly and freely available server for 3D structure prediction of RNA up to 500 nucleotide residues. RNAComposer employs fully automated fragment assembly based on RNA secondary structure specified by the user. Importantly, this method allows incorporation of distance restraints derived from the experimental data to strengthen the 3D predictions. The potential and limitations of RNAComposer are discussed and an application to RNA design for nanotechnology is presented.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Marcin Biesiada, Katarzyna Pachulska-Wieczorek, Ryszard W. Adamiak, Katarzyna J. Purzycka,