| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8340379 | Methods | 2016 | 6 Pages |
Abstract
The localization of a protein is intrinsically linked to its role in the structural and functional organization of the cell. Advances in transgenic technology have streamlined the use of protein localization as a function discovery tool. Here we review the use of large genomic DNA constructs such as bacterial artificial chromosomes as a transgenic platform for systematic tag-based protein function exploration.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Susanne Hasse, Anthony A. Hyman, Mihail Sarov,