Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8340425 | Methods | 2016 | 6 Pages |
Abstract
We compare the response of multicellular spheroids, individual cells and matrigel to the same osmotic perturbation. Our findings indicate that the osmotic pressure occasioned by polymers acts on these systems like an isotropic mechanical stress. When submitted to this pressure, the volume of multicellular spheroids decreases much more than one could expect from the behavior of individual cells.
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Authors
Sylvain Monnier, Morgan Delarue, Benjamin Brunel, Monika E. Dolega, Antoine Delon, Giovanni Cappello,