Article ID Journal Published Year Pages File Type
8340456 Methods 2015 7 Pages PDF
Abstract
The functions of many viral proteins involve direct interactions with specific host proteins. Therefore considerable insight into the functions of a viral protein and its mechanisms of action can come from applying proteomics approaches to viral proteins in order to identify their cellular binding partners. In this chapter we describe proteomics approaches that have proven to be the most useful in identifying host interactions of viral proteins in human cells. Caveats and potential alternatives for each step are also discussed.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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