| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8341223 | Microvascular Research | 2015 | 6 Pages |
Abstract
In this work, we demonstrate that a HR6 scFv selected from human library phage display specifically blocks VEGF signaling, furthermore, this scFv has an anti-angiogenesis effect and because of its small size has more tissue diffusion. The HR6 antibody was isolated form a human library thus, it is not immunogenic for humans and could serve as a potential therapeutic agent in cancer.
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Authors
Hossien Hosseini, Masoumeh Rajabibazl, Walead Ebrahimizadeh, Gholamreza Rafiei Dehbidi,