| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8342968 | Molecular Genetics and Metabolism | 2018 | 29 Pages |
Abstract
Findings suggest that decline in ARSB activity caused by decline in CFTR function leads to increased GPNMB, which may contribute to organ dysfunction in CF by increased MMP-9 expression.
Keywords
C4SN-Acetylgalactosamine-4-sulfataseBECGPNMBMMP-9ERKARSBSHP2CFTRGAGMITFMAPKS.D.standard deviationcystic fibrosis transmembrane conductance regulatorBronchial epithelial cellsDermatan sulfateSulfataseCystic fibrosismitogen-activated protein kinasechondroitin 4-sulfateextracellular signal-regulated kinaseGlycosaminoglycansGlycosaminoglycan
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Authors
Sumit Bhattacharyya, Leo Feferman, Girish Sharma, Joanne K. Tobacman,