Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8344193 | Molecular Genetics and Metabolism | 2011 | 8 Pages |
Abstract
Transdifferentiation of an individual's own cells into functional differentiated cells to replace an organ's lost function would be a personalized approach to therapeutics. In this two part series, we will describe the progress toward establishing functional transdifferentiated adrenal cortical cells. In this article (Part 1), we describe adrenal development and function, and discuss genes involved in these processess and selected for use in our pilot studies of transdifferentiation that are presented in the second article (Part 2).
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Authors
Jaime K. Mazilu, Edward R.B. McCabe,