Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8346150 | Nitric Oxide | 2013 | 7 Pages |
Abstract
⺠We used the model of hepatotoxicity (GalN) in rats to test the protective effect of F1,6BP. ⺠The administration of F1,6BP abolished the liver injury in rats treated with d-GalN. ⺠We tested the effect of l-Name (NOS inhibitor) in the protection induced by F1,6BP. ⺠l-NAME reversed the protection induced by F1,6BP en rats treated with d-GalN. ⺠F1,6BP induced an increase in NO and the redox ratio (GSH/GSSG) in liver.
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Authors
Norma Alva, David Cruz, Sergio Sanchez, Juana Ma ValentÃn, Jordi Bermudez, Teresa Carbonell,