| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8347338 | Peptides | 2018 | 26 Pages |
Abstract
Bradykinin-potentiating peptides (BPPs - 5a, 7a, 9a, 10c, 11e, and 12b) of Bothrops jararaca (Bj) were described as argininosuccinate synthase (AsS) activators, improving l-arginine availability. Agmatine and polyamines, which are l-arginine metabolism products, have neuroprotective properties. Here, we investigated the neuroprotective effects of low molecular mass fraction from Bj venom (LMMF) and two synthetic BPPs (BPP-10c,â
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Authors
Samyr Machado Querobino, César Augusto João Ribeiro, Carlos Alberto-Silva,