Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8347354 | Peptides | 2018 | 7 Pages |
Abstract
Our findings show that chemosensory cells within CBs express V1aRs and that local stimulation of the CB with AVP increases ventilation, which is contrary to systemic effects of AVP manifested by decreased ventilation. The responses are mediated by V1aRs, as blockade of the receptors prevents changes in ventilation. We hypothesize that excitatory effects of AVP within the CB provide a counterbalancing mechanism for the inhibitory effects of systemically acting AVP on the respiration.
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Authors
Tymoteusz Å»era, Jacek Przybylski, Tomasz Grygorowicz, Kaja KasareÅÅo, Martyna PodobiÅska, Dagmara Mirowska-Guzel, Agnieszka Cudnoch-JÄdrzejewska,