| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8347370 | Peptides | 2018 | 29 Pages |
Abstract
These results demonstrate a direct effect of INGAP-PP on the liver acting through P-Akt signaling pathway. INGAP-PP enhances liver glucose metabolism and deposit and reduces its production/output, thereby contributing to maintain normal glucose homeostasis. These results reinforce the concept that INGAP-PP might become a useful tool to treat people with impaired islet/liver glucose metabolism as it occurs in T2D.
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Authors
Hernán Gonzalo VillagarcÃa, Carolina Lisi Román, MarÃa Cecilia Castro, Luisa Arbeláez González, MarÃa Teresa Ronco, Daniel Eleazar Francés, MarÃa Laura Massa, Bárbara Maiztegui, Luis Emilio Flores, Juan José Gagliardino, Flavio Francini,