| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8347996 | Peptides | 2015 | 10 Pages |
Abstract
- N-terminal derivatives of a frog skin peptide with anti-Pseudomonal/Candida activity.
- The mechanism relies on a fast membranolytic action on planktonic and biofilm forms.
- In vivo efficacy in murine models of lung/ocular Pseudomonas-induced infection.
- Ability to block Candida hyphal formation in a whole living organism.
- Promising candidates for new anti-infectives in human and veterinary medicine.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Maria Luisa Mangoni, Vincenzo Luca, Alison M. McDermott,