Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8348051 | Peptides | 2015 | 9 Pages |
Abstract
- HNTX-IV is an antagonist of Nav1.7 with high selectivity over other VGSC subtypes.
- The binding site for HNTX-IV was determined as the S3-S4 linker of Nav1.7 domain II.
- The toxin-channel complex was constructed by in silico docking.
Keywords
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Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Tianfu Cai, Ji Luo, Er Meng, Jiuping Ding, Songping Liang, Sheng Wang, Zhonghua Liu,