| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8348110 | Peptides | 2015 | 9 Pages |
Abstract
Our results indicate that RE down-regulates CB1 expression. Inhibition of CB1 signaling increases skeletal muscle anabolic signaling down-stream of mTOR and protein synthesis through ERK1/2. Our study may provide base for the development of CB1-blocking drugs to treat or prevent muscle wasting.
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Authors
Satu Pekkala, Petri Wiklund, Juha J. Hulmi, Eija Pöllänen, Varpu Marjomäki, Eveliina Munukka, Philippe Pierre, Vincent Mouly, Antti Mero, Markku Alén, Sulin Cheng,