Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8348673 | Peptides | 2013 | 7 Pages |
Abstract
- Antimicrobial activity of pleurocidin is retained in a C-terminal 12-amino acid fragment.
- The antifungal effects of Plc-2 are thought to be due to membrane disruption after the accumulation in the plasma membrane of the fungal cell.
- This peptide may be helpful to form a leading model for developing new and of novel therapeutic agents.
Keywords
PBSminimal fungicidal concentrationPleurocidinBHIAMPsCFWPLCSYTOX greenMBCTBSMICPDBCDIMFCPDACFUMHbethidium bromideMinimal bactericidal concentrationMinimal inhibitory concentrationpotato dextrose agarpotato dextrose brothbrain heart infusion brothPhosphate buffered salineAntifungal activityMALDIcolony-forming unitsPore-formingSynthetic peptidesAntimicrobial peptidesCationic peptideshigh performance liquid chromatographyHPLCcalcofluor WHITE
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Biochemistry
Authors
Andre L.A. Souza, Paola DÃaz-Dellavalle, Andrea Cabrera, Patricia Larrañaga, Marco Dalla-Rizza, Salvatore G. De-Simone,