Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8348739 | Peptides | 2013 | 12 Pages |
Abstract
⺠GLP-1, GLP-2 and glucagon share a common precursor but have divergent functions. ⺠A complex inter-dependent relationship exists between GLP-1 secretion, postprandial glycemia and gastric emptying. ⺠GLP-1 agonists retard gastric emptying. ⺠GLP-1 could be exploited therapeutically for its extra-intestinal effects. ⺠GLP-2 shows promise as an intestinotropic agent.
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Authors
Chinmay S. Marathe, Christopher K. Rayner, Karen L. Jones, Michael Horowitz,