Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8348783 | Peptides | 2013 | 8 Pages |
Abstract
⺠We firstly demonstrated the distribution sites of r/m HK-1 in mouse brain. ⺠The analgesia of r/m HK-1 is induced by the activation of NK1 receptor firstly. ⺠The analgesia of r/m HK-1 is also related to the expression increase of MOR and POMC.
Keywords
MORRat/mouse hemokinin-1ProenkephalinpDynPOMCFAMGAPDHPPTδ-Opioid receptorμ-Opioid receptorTranscriptional expressionProtein expressionIntracerebroventricular administrationDORKORproopiomelanocortinprodynorphinPreprotachykininPENKcarboxyfluoresceinglyceraldehyde-3-phosphate dehydrogenaseκ-opioid receptor
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Authors
Rui-Long Xia, Cai-Yun Fu, Shi-Fu Zhang, Yuan-Ting Jin, Fu-Kun Zhao,