Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8348824 | Peptides | 2013 | 7 Pages |
Abstract
⺠Rat overexpressing the B1R specifically in the vascular endothelium were assessed. ⺠The BK-induced relaxations were significantly increased in the transgenic rats. ⺠The expression level of the B2R in the transgenic rats was highly increased. ⺠The ACE activity and mRNA ACE expression was not altered. ⺠We report that the B2R expression is upregulated by the overexpression of B1R.
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Authors
Eliete S. Rodrigues, Rafael F. Silva, Renan P. Martin, Suzana M. Oliveira, Clovis R. Nakaie, Regiane A. Sabatini, Vanessa F. Merino, João B. Pesquero, Michael Bader, Suma I. Shimuta,