| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8348831 | Peptides | 2013 | 10 Pages |
Abstract
⺠The endogenous levels of ACE2 and the Mas receptor were increased in calcified aortas. ⺠Ang-(1-7) inhibited the development of vascular calcification in rats. ⺠Ang-(1-7) prevented the loss of lineage markers and attenuated the osteogenic transition of vascular smooth muscle cells. ⺠Ang-(1-7) reversed the upregulated levels of the ACE/Ang II/AT1 axis in calcified arota.
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Authors
Yu-Bin Sui, Jin-Rui Chang, Wen-Jia Chen, Lei Zhao, Bao-Hong Zhang, Yan-Rong Yu, Chao-Shu Tang, Xin-Hua Yin, Yong-Fen Qi,