Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8352097 | Pharmacology Biochemistry and Behavior | 2013 | 7 Pages |
Abstract
⺠Safinamide is an MAO B inhibitor with additional non-dopaminergic actions. ⺠Safinamide was tested for anti-tremor effects in the tremulous jaw movement model. ⺠Safinamide blocked tremor induced by cholinomimetics and dopamine antagonism. ⺠Safinamide may be useful for treating tremors in parkinsonism and other disorders.
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Authors
Samantha Podurgiel, Lyndsey E. Collins-Praino, Samantha Yohn, Patrick A. Randall, Arthur Roach, Christophe Lobianco, John D. Salamone,