Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8352114 | Pharmacology Biochemistry and Behavior | 2013 | 8 Pages |
Abstract
⺠Senescence-accelerated mouse prone 8 (SAMP8), an animal model of Alzheimer's disease ⺠SAMP8 showed learning and memory deficit, inflammation and oxidative stress. ⺠Forsythiaside has improved cognitive impairments in aged SAMP8 mice. ⺠Forsythiaside has decreased inflammatory cytokines (interleukins 1 and 6) in brain. ⺠Forsythiaside has suppressed oxidative stress in brain.
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Authors
Hong-Mei Wang, Li-Wei Wang, Xin-Min Liu, Chang-Lu Li, Shu-Ping Xu, Ahsana-Dar Farooq,