Dissociated modulation of conditioned place-preference and mechanical hypersensitivity by a TRPA1 channel antagonist in peripheral neuropathy

Article ID	Journal	Published Year	Pages	File Type
8352237	Pharmacology Biochemistry and Behavior	2013	7 Pages	PDF

Abstract

âº Blocking the TRPA1 channel failed to produce place reference in peripheral neuropathy. âº Blocking TRPA1 attenuated mechanical hypersensitivity in peripheral neuropathy. âº Ongoing neuropathic pain is less sensitive to blocking TRPA1 than hypersensitivity.

Keywords

Transient receptor potential ankyrin 1 channel Peripheral nerve injury Mechanical hypersensitivity Ongoing pain conditioned place-preference diabetic neuropathy clonidine

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

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Dissociated modulation of conditioned place-preference and mechanical hypersensitivity by a TRPA1 channel antagonist in peripheral neuropathy

Authors

Hong Wei, Hanna Viisanen, Diana Amorim, Ari Koivisto, Antti Pertovaara,