Article ID Journal Published Year Pages File Type
8352291 Pharmacology Biochemistry and Behavior 2013 8 Pages PDF
Abstract
► Evaluation of locomotor activity, nicotine self-administration and gene expression. ► Molecular assays to evaluate gene expression in the nucleus accumbens. ► Cocaine caused locomotor sensitization and cross-sensitization with nicotine. ► Repeated cocaine injections increased the break point and total nicotine intake. ► Cocaine and nicotine interaction increased BDNF gene expression in the accumbens.
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