Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8361165 | Regulatory Peptides | 2013 | 6 Pages |
Abstract
The observations confirmed the absence of an acute stimulatory effect of central leptin on serotonin release in the lateral hypothalamus and showed that the pre-treatment with leptin failed to modify this pattern. This indicates that components of the serotonergic system are probably not directly affected by leptin. Additionally, the central effect of leptin was able to downregulate its own adipose tissue gene expression in a depot-specific manner while other adipokine genes were not affected.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Mônica Marques Telles, ThaÃs Girão da Silva, Regina Lúcia Harumi Watanabe, Iracema Senna de Andrade, Debora Estadella, Cláudia Maria Oller Nascimento, Lila Missae Oyama, Eliane Beraldi Ribeiro,