| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8361223 | Regulatory Peptides | 2013 | 7 Pages |
Abstract
⺠Tonin is able to generate the pressor octapeptide Ang II in the isolated rat heart. ⺠Tonin increased blood pressure and heart rate and decreased heart rate variability. ⺠Tonin induced increase in arterial coronary pressure and negative inotropic effects. ⺠The cardiovascular responses induced by tonin were completely blocked by candesartan.
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Authors
Denis D. Damasceno, Mercia P. Lima, Daisy F. Motta, Anderson J. Ferreira, Judson F. Quintão-Junior, Lucas R. Drummond, Antônio J. Natali, Alvair P. Almeida, Jorge L. Pesquero,