Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8361299 | Regulatory Peptides | 2012 | 10 Pages |
Abstract
⺠GLP-1 receptor agonists and DPP-4 inhibitors are extensively used as anti-diabetic drugs. ⺠We investigated if GLP-RAs and a DPP-4 inhibitor had trophic effects in the mouse intestine. ⺠We also investigated if a GLP-RA and a DPP-4 inhibitor had tumour promoting effects in the colon of carcinogen treated mice. ⺠GLP-1 RAs significantly increased intestinal growth, but we found no tumour promoting effect in the colon.
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Authors
Hannelouise Kissow, Bolette Hartmann, Jens Juul Holst, Niels-Erik Viby, Lærke Schmidt Hansen, Mette Marie Rosenkilde, Kristine Juul Hare, Steen Seier Poulsen,