| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8361326 | Regulatory Peptides | 2012 | 8 Pages |
Abstract
⺠Angiotensin II infusion for 6 days induces cachexia in mice. ⺠Ghrelin increases food intake and body weight in angiotensin II treated mice. ⺠Ghrelin also inhibits the expression of catabolic factor mRNA in the skeletal muscle. ⺠The short-term administration of ghrelin increases IGF-1 mRNA in the skeletal muscle. ⺠Early reversal of IGF-1 mRNA in the skeletal muscle could improve muscle catabolism.
Keywords
MuRF1ChFDMEMDEXFBSGAPDHRT-PCRGHS-RIGF-1Dulbecco's modified Eagle's mediumAngiotensin IIstandard errorsintraperitonealAng IIDexamethasonesubcutaneousfetal bovine seruminsulin-like growth factor 1Chronic heart failureGrowth hormonebody weightMuscle catabolismCachexiaGhrelinglyceraldehyde 3-phosphate dehydrogenasegrowth hormone secretagogue receptor
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Authors
Masako Sugiyama, Akira Yamaki, Mayumi Furuya, Norio Inomata, Yoshiharu Minamitake, Kazuhiro Ohsuye, Kenji Kangawa,