| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8361344 | Regulatory Peptides | 2012 | 8 Pages |
Abstract
⺠Chronic 2K1C rats showed hypertension and signs of cardiac failure. ⺠Apelin reduced BP and increased cardiac contractility indices in chronic 2K1C rats. ⺠Serum apelin reduced and aldosterone increased in chronic 2K1C hypertension. ⺠Apelin in medium and high doses induced opposite myocardial inotropic effects. ⺠Chronic 2K1C decreased apelin receptor mRNA and protein expression in both kidneys.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Hamid Najafipour, Ava Soltani Hekmat, Ali Akbar Nekooian, Saeed Esmaeili-Mahani,