Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8361367 | Regulatory Peptides | 2012 | 9 Pages |
Abstract
⺠We examine the physiologic role of BDNF synergistic with SP/CGRP on mouse gut motility. ⺠We clarify the excitatory effects of SP and bilateral effects of CGRP on the contraction of LM strips. ⺠Pretreatment with exogenous BDNF enhances the contraction of LM strips induced by SP and CGRP. ⺠Reduction of endogenous BDNF attenuated the contraction of LM strips induced by SP and CGRP. ⺠BDNF accelerates gut motility by enhancing the excitatory effects of SP/CGRP.
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Authors
Fei-xue Chen, Yan-bo Yu, Xue-min Yuan, Xiu-li Zuo, Yan-qing Li,