| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8361377 | Regulatory Peptides | 2012 | 11 Pages |
Abstract
⺠Our data highlight mechanisms of modulation of insulin signaling by Ang-(1-7). ⺠Ang-(1-7) reverts acute in vivo Ang II-mediated inhibition of insulin signaling. ⺠Ang-(1-7) restores insulin signaling in fructose-fed rats. ⺠These actions of Ang-(1-7) disappear in presence of a Mas receptor antagonist. ⺠Our data shows that Ang-(1-7) modulates insulin action through the Mas receptor.
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Authors
Marina C. Muñoz, Jorge F. Giani, Valeria Burghi, Marcos A. Mayer, Andrea Carranza, Carlos A. Taira, Fernando P. Dominici,