Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8361390 | Regulatory Peptides | 2012 | 5 Pages |
Abstract
⺠The GLP-1R agonist liraglutide is an effective anti-diabetic agent. ⺠We investigated changes in islet blood flow, insulinemia and glycemia in GK rats. ⺠Liraglutide reduced body weight gain and improved glucose tolerance. ⺠Liraglutide halts the natural progression towards diabetes in GK rats. ⺠Liraglutide does not affect islet microcirculation or pancreatic insulin content.
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Authors
Lin Wu, Anna Olverling, Liselotte Fransson, Henrik Ortsäter, Camilla Kappe, Xin Gao, Ã
ke Sjöholm,