| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8361406 | Regulatory Peptides | 2012 | 4 Pages |
Abstract
⺠Heregulin-β1 has preventive effects on the development of atherosclerosis and restenosis. ⺠This peptide suppresses macrophage foam cell formation and vascular smooth muscle cell proliferation. ⺠This peptide activates endothelial nitric oxide synthase and has anti-inflammatory and cardioprotective effects. ⺠This peptide is also a candidate biomarker for coronary artery disease. ⺠Heregulin-β1 is, therefore, useful for the diagnosis and treatment of atherosclerotic cardiovascular diseases.
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Authors
Takuya Watanabe, Kengo Sato, Fumiko Itoh, Yoshitaka Iso,