| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8361473 | Regulatory Peptides | 2012 | 9 Pages |
Abstract
⺠Exogenous ghrelin was shown to stimulate food intake via the energy sensor AMPK and UCP2. ⺠Does a rise in endogenous ghrelin influence AMPK, pACC, UCP2 and NPY/AgRP through GHS-R? ⺠A rise in endogenous ghrelin stimulates NPY and AgRP in GHS-R+/+, not in GHS-Râ/â mice. ⺠AMPK, pACC and UCP2 were not influenced by the genotype and change independently from GHS-R. ⺠AMPK and its downstream targets may not play a major role in the effect of endogenous ghrelin.
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Authors
P.J. Verhulst, S. Janssen, J. Tack, I. Depoortere,