Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8361479 | Regulatory Peptides | 2012 | 8 Pages |
Abstract
⺠We studied the action of apelin-12 on the secretion of gastric acid. ⺠Apelin-12 increased acid output in gastric lumen-perfused rat stomachs. ⺠Famotidine, inhibited apelin-12-stimulated acid secretion. ⺠Apelin-12 stimulated histamine secretion and synthesis in rat stomachs. ⺠The results indicate that apelin plays a role in the secretion of gastric acid.
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Authors
Shino Ohno, Koji Yakabi, Shoki Ro, Mitsuko Ochiai, Tsuneko Onouchi, Tomoya Sakurada, Hidehiko Takabayashi, Shuko Ishida, Kiyoshige Takayama,