Article ID Journal Published Year Pages File Type
8361481 Regulatory Peptides 2012 11 Pages PDF
Abstract
► Putative GTPase-activating protein IQGAP2 has a novel role in fatty acid metabolism. ► Iqgap2-deficient mice are protected against diet-induced fatty liver. ► Iqgap2−/− hepatocytes display a loss of the facilitated phase of fatty acid uptake.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Ablation of Iqgap2 protects from diet-induced hepatic steatosis due to impaired fatty acid uptake
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