Article ID Journal Published Year Pages File Type
8361499 Regulatory Peptides 2012 4 Pages PDF
Abstract
► A long-term high-fat diet in rats has a persistent inhibitory effect on basal plasma ghrelin levels. ► The plasma ghrelin elevation to an overnight fast persists in rats fed a high-fat diet for a long-term basis. ► A high-fat diet does not inhibit the ingestive response to ghrelin. ► Insulin does not inhibit the plasma ghrelin response to fasting. ► Pioglitazone treatment increases stomach ghrelin homeostasis in rats fed a high-fat diet.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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Influence of a long-term high-fat diet on ghrelin secretion and ghrelin-induced food intake in rats
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