| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8361561 | Regulatory Peptides | 2011 | 7 Pages |
Abstract
⺠Apelin at dose 20ug/kg increased +LVdp/dt max and -LV dp/dt max of the heart. ⺠Apelin at dose 40ug/kg strongly decreased SBP, DBP, and the above two indices. ⺠2K1C did not change apelin, aldosterone and AVP levels but increased angII level. ⺠2K1C decreased apelin receptor mRNA and protein expression in non- cliped kidney. ⺠Apelin with RAS antagonism may be useful therapeutic goals in 2K1C hypertension.
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Authors
Ava Soltani Hekmat, Hamid Najafipour, Ali Akbar Nekooian, Saeed Esmaeli-Mahani, Kazem Javanmardi,