Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8361588 | Regulatory Peptides | 2011 | 7 Pages |
Abstract
⺠The preventive effects of CGRP on BBB permeability and cerebral edema were investigated in cerebral ischemia reperfusion rat. ⺠The results showed that CGRP could reduce BBB permeability and cerebral edema. ⺠CGRP could decrease arterial blood pressure and infarct volume. ⺠CGRP could inhibit aquaporin-4 and its mRNA expression. ⺠CGRP may play an role in improving ultrastructural damage of capillary endothelial cells.
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Authors
Zhen Liu, Qian Liu, Heng Cai, Chunsheng Xu, Guixiang Liu, Zhenzhong Li,