Article ID Journal Published Year Pages File Type
8361652 Regulatory Peptides 2011 6 Pages PDF
Abstract
► GLP-1(28-36)amide, derived from GLP-1, has insulin-like actions in obese mice. ► The nonapeptide inhibits weight gain and the development of insulin resistance. ► It also attenuates diabetes and hepatic steatosis. ► No effects of GLP-1(28-36)amide are seen in normal lean, insulin-sensitive mice. ► GLP-1(28-36)amide might be a treatment for metabolic syndrome.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
GLP-1-derived nonapeptide GLP-1(28-36)amide inhibits weight gain and attenuates diabetes and hepatic steatosis in diet-induced obese mice
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