Article ID Journal Published Year Pages File Type
8361654 Regulatory Peptides 2011 9 Pages PDF
Abstract
► Cardioprotection by ischemic postconditioning (IPostC) is lost in diabetic hearts. ► The loss of cardioprotection by IPostC during diabetes is partly associated with a failure to increase CGRP and SP release, likely due to decreased TRPV1 expression and CGRP and SP contents in diabetic hearts. ► Exogenous application of CGRP or SP can restore the cardioprotection by IPostC in diabetic hearts.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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